Articles

Plain-language comparisons, explainers and the legal status of popular peptides. Every claim is numbered to its source.

  1. Explainer

    Compounded vs approved GLP-1 drugs: what is the difference?

    Approved semaglutide and tirzepatide are FDA-reviewed; compounded versions are not. How the 503A and 503B rules work and what changed after the shortages.

  2. Explainer

    How to judge the evidence behind a peptide claim

    Why a randomised trial in people outweighs a study in rats, what approval does and does not tell you, and how PeptoKing grades the evidence for each peptide.

  3. Legal status

    Is BPC-157 legal? Status in the US, UK, EU, Australia and Canada

    BPC-157 is not an approved medicine in the US, UK, EU, Australia or Canada. What each regulator says about selling it, and its status in sport.

  4. Comparison

    Retatrutide vs tirzepatide: what the trials show and what they don't

    Retatrutide is an unapproved triple agonist; tirzepatide is approved. How they work, trial results, why cross-trial numbers mislead, and online product risks.

  5. Comparison

    Semaglutide vs tirzepatide: what the SURMOUNT-5 head-to-head trial showed

    Semaglutide (Wegovy, Ozempic) vs tirzepatide (Zepbound, Mounjaro): how they work, approvals, the SURMOUNT-5 trial, heart outcome data and label warnings.

  6. Explainer

    What does 'research use only' mean on peptides?

    A 'research use only' label is not an approval. What regulators in the US, Canada, Australia and the UK say about it, and what product testing has found.